Rosie’s Journey
“I need to look at the sunshine and know that I will see it for years to come. I need to believe these things.”
“I need to look at the sunshine and know that I will see it for years to come. I need to believe these things.”
We want to put secondary breast cancer first. Front of mind. Top of the list. This is a disease that has spread to the rest of the body. It affects men and women everywhere. Finding a cure means a diagnosis is no longer the end. It means people will have more days doing what matters most. It means daughters, mothers, fathers and sons will go on living a life they love.
When cancer cells in the breast spread to other parts of the body via the blood stream, lymph system, or body cavities, it is called secondary (metastatic) breast cancer. These new tumours are made up of breast cancer cells.
Keep up to date on Secondary1st news and breast cancer research.
The NHS in England has started offering liquid biopsies to some women with breast cancer that has mutated. These circulating tumour DNA (ctDNA) blood tests will show whether women with ER-positive HER2 negative secondary breast cancer have developed the ESR1 mutation which can sometimes occur after long-term treatment with hormone therapy. ER-positive cancer cells are…
Olaparib (Lynparza) has now been approved by NICE as a second-line treatment of HER2-negative locally advanced or metastatic breast cancer in adults with mutated BRCA1 or BRCA2 genes who have had chemotherapy. Olaparib is a PARP inhibitor; PAPR is a protein which helps cancer cells repair themselves and Olaparib stops this repair process in these…
In 2024 thanks to donors and fundraisers Secondary1st funded the first year of a research project led by Professor Simak Ali at Imperial College London investigating how changes in the ER gene contribute to hormone therapy resistance. About 44,000 people are diagnose with ER (oestrogen receptor) positive breast cancer each year in the UK and…
Secondary1st is run by a team of dedicated volunteers. We’re always looking for a pair of extra hands to help with the charity, particularly with fund raising efforts. If you’d like to get involved please get in touch!