A Nice New Drug

Olaparib (Lynparza) has now been approved by NICE as a second-line treatment of HER2-negative locally advanced or metastatic breast cancer in adults with mutated BRCA1 or BRCA2 genes who have had chemotherapy. Olaparib is a PARP inhibitor; PAPR is a protein which helps cancer cells repair themselves and Olaparib stops this repair process in these…

Research Update

In 2024 thanks to donors and fundraisers Secondary1st funded the first year of a research project led by Professor Simak Ali at Imperial College London investigating how changes in the ER gene contribute to hormone therapy resistance. About 44,000 people are diagnose with ER (oestrogen receptor) positive breast cancer each year in the UK and…