Nolan’s Latest Challenge

It seemed a long time ahead when Nolan signed up for it but, after several months of getting up at 5am to train, his cycle ride from Land’s End to John O’Groats is only four weeks away. He will ride through some his favourite places on a journey of over 1,000 miles which will include…

Professor Seth Coffelt

Seth Coffelt, who leads the team at the Beatson Institute for Cancer Research at the University of Glasgow which has received funding for the past three years through the generosity of Secondary1st fundraisers and donors, has been appointed Professor of Cancer Immunology at the University of Glasgow. Professor Coffelt and his team have been studying…

John: Another 3 Peaks Challenge

In 2020 in the middle of the pandemic Angela, who had been diagnosed with secondary breast cancer the previous year, completed the 2.6 challenge by walking for 26 miles on her old cross trainer. Two years later her son John finished the 3 Peaks Challenge to raise money for Secondary1st. This year John has completed…

Superhero Tim Did It Again

Just three weeks after finishing in the Brighton Marathon Superhero Tim completed the London Marathon. Marathons, skydiving, fitness challenges… there seems no end to the adventures Tim undertakes to raise money for Secondary1st. He is one of our all-time superheroes.

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AI in Experiment to Predict if Breast Cancer Will Spread

A team of scientists at King’s College London has developed an Artificial Intelligence model which analyses immune responses in the lymph nodes to predict the likelihood of developing secondary breast cancer for patients with triple negative breast cancer. Lymph nodes are small bean-shaped structures that are part of the body’s immune system. They filter substances…

Nolan Comes to Land

Last year Nolan rode a zipwire to raise money for Secondary1st. This year he’s planning to undertake a more down to earth challenge. In September he will cycle more than 1000 km, riding all the way from Land’s End to John O’Groats, travelling from one end of the country to the other. He is training…

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Another NICE Story

In June 2022 we reported that favourable results from a trial of a new cancer drug, Enhertu (trastuzumab deruxtecan), had been presented at this year’s meeting of the American Society of Clinical Oncology and had been published in the “New England Journal of Medicine”. Enhertu is a specifically engineered HER-2-directed antibody drug conjugate which has…

Some More Good News

Dr Coffelt and his team at the Beatson Institute for Cancer Research in Glasgow in another project funded by Secondary1st’s fundraisers and donors are working to understand why existing immunotherapies are less effective in treating breast cancer than other cancer types. They recently published a report on a significant discovery that breast cancer immunotherapy could…

Some Good News at the End of the Year

At the University of Bradford in one of the projects funded by the wonderful donors and fundraisers of Secondary1st Professor Pors and his PhD student Enrica are continuing their work to improve duocarmycins, a very effective but highly toxic chemotherapy, so that they can be used to treat breast cancer. In the second year of…